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Interaction of Lexapro with other drugs
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At the same time taking with MAO inhibitors increase the risk of serotonin syndrome and serious adverse reactions. The combined use of serotoninergic drugs (including those with tramadol, sumatriptanom triptanami etc.) can lead to serotonin syndrome. Simultaneous reception with drugs, lowers the threshold of convulsive readiness, increases the risk of seizures.
Enhances the effect of tryptophan and preparations Li +. Increases toxicity of Hypericum preparations. Enhances the effect of drugs affecting blood clotting (requires monitoring of indicators of blood coagulation). Drugs, is metabolized with the participation of CYP2S19 (including omeprazole), and is a strong inhibitor CYPZA4 and CYP2D6 (including flekainid, propafenone, metoprolol, desipramine, clomipramine, Nortriptyline, risperidone, tioridazin, haloperidol), increase concentration estsitaloprama. Increases in plasma concentration of desipramine and metoprolol 2 times.